AstraZeneca: positive phase 3 results with Ionis


(CercleFinance.com) – Ionis Pharmaceuticals announced on Wednesday that eplontersen, the treatment for familial amyloid polyneuropathy it is developing with AstraZeneca, has met its primary endpoint in phase 3 clinical trials.

The American biopharmaceutical group indicates that the drug provided a “statistically significant and clinically satisfactory” improvement in patients with transthyretin amyloid neuropathy (NAH-TTR) compared to a placebo.

These results – presented at a scientific congress in Heidelberg (Germany) – showed an 81.2% reduction in the level of transthyretin in patients who received treatment.

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